Type 3 diabetes

The holidays are famous for classic re-runs and bad sequels, but I didn’t expect to find Type 3 Diabetes. This is the concept linking insulin resistance and Alzheimer dementia. Neurons have some insulin-dependent glucose receptors which become resistant in diabetes such that neurons are insidiously deprived of glucose, compromising their function. Meanwhile, dyslipidemia leads lipids to cross the blood brain barrier and further toxify neurons. Likewise nitrosamines in cooked and cured meats are implicated in the development of amyloid beta and tao proteins as well as in aggravating brain insulin resistance. Dr. Suzanne De La Monte has been a leader in Type 3 diabetes research since the early 2000’s. She chronicles the journey in this fascinating piece.

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad170829