Inflammation is what food can either promote or prevent. Adipose tissue is an active endocrine organ that releases adipokines, triggering immune cells to release inflammatory cytokines. In the musculoskeletal system, this tips joints into a catabolic state of degeneration. So in obesity there is increased loading on joints AND intrinsic breakdown. This is why whole-food plant-based eating is so powerful. It facilitates weight loss AND reduces inflammation for musculoskeletal and rheumatologic pain relief. This article expands on the mechanisms: https://www.mdpi.com/1422-0067/20/8/2030